Signs & Symptoms
GENERAL SYSTEM
Scroll down to see some of the signs & symptoms that a vitamin B12 deficiency can cause in the GENERAL SYSTEM areas of the body.
To see the possible signs & symptoms of other areas of the body just click on the appropriate button on the diagram below.
Symptoms underlined and highlighted in the same colour as their body area can be clicked on to see documented and peer reviewed sources of information.
Because neurological symptoms of vitamin B12 deficiency can cause irreversible damage if left untreated, we have also indicated which of the symptoms are neurological by putting this (N) next to them.

GENERAL SYSTEM
Musculoskeletal
Haematological/Vascular
Blood Signs & Symptoms
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Anaemia
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Hyper Segmented Neutrophils (Diagnostic Feature of Megaloblastic Anaemia)
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Macrocytosis (Enlarged Red Blood Cells)
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Pallor/Jaundice
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Suppressed activity of Osteoblasts (Bone Building Cells)
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Weakness
Vascular Signs & Symptoms
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Bruising
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Orthostatic Hypotension, Postural Hyptention (Low Blood Pressure on Standing)
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Vasculitis
Pain
Neurological/Inflammation
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Chronic Pain Disorder (N)
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Inflammatory joint Pain
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Impaired Pain Perception (N)
Bone Issues
Skin & Hair
Textural Changes
Sensory
Altered Sensation
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Burning/Cold Sensations (N)
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Creepy Crawly Sensations on Skin (N)
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Heat and/or Cold Intollerance (Incl. Night Sweats)
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Impaired Proprioception (Body Position) (N)
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Itching (N)
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Impaired Vibration Sense (N)
Paresthesia
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Tingling Sensation (N)
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Numbness (N)
Other Common Signs & Symptoms
Other General Symptoms
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Chronic Fatigue
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Compromised Immune System (Prone to Infections)
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Loss of Appetite/Unintentional Weight Loss
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Malaise/General Feeling of Being Unwell
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Malnutrition/Other Nutrient Deficiencies
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Nausea
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Poor Wound Healing
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Symptoms Similar to Parkinson's Disease. Alzheimer's and Multiple Sclerosis (N)
Movement
Movement Disorders
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Abnormal Reflexes (N)
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Involuntary Movements/Chorea (N)
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Muscular Stiffness/Tightness (N)
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Tremor (N)
